We'll be moving into our first house next month, so there should be some activity here in the next few months as I will actually have the opportunity to do some in-depth home automation. There's no basement, but the crawlspace is fairly large, so I should be able to run first floor wires without too much problem. I'm trying to start work on a layout now, so I may post that once I finish.
At this point I'm planning to use MisterHouse again because of the unlimited flexibility, although I haven't really looked around lately, so I'm not what what's out there. I'll probably start out with the modules I have, and then move on to the network, light switches and thermostats. I'll probably try to put the Audrey in the living room or bedroom, and a laptop in the the other. A security system will probably be coming as well...